Larange A, Takazawa I, Kakugawa K, Thiault N, Olive ME, Ngoi S, Iwaya H, Seguin L, Vicente-Suarez I, Becart S, Altman A, Taniuchi I, Chang JT, Lillemeier BF, Kronenberg M, Myers SA, Cheroutre H. (2023) T cell activation is spatially and temporally controlled by extranuclear and nuclear RAR α. Immunity Aug 13;S1074-7613(23)00330-8.
Russ M, Ehret AK, Hörner M, Peschkov D, Bohnert R, Idstein V, Minguet S, Weber W, Lillemeier BF, Yousefi OS, Schamel WW. (2023) Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions. Front Mol Biosci. Feb 20;10:1143274.
Gunasekara H, Munaweera R, Novotná L, Lillemeier BF*, Hu YS*. (2022) Chaotropic Perturbation of Noncovalent Interactions of the Hemagglutinin Tag Monoclonal Antibody Fragment Enables Superresolution Molecular Census. ACS Nano. Jan 25;16(1):129-139. (*co-corresponding author)
Lillemeier BF. CARs need a jump start to get going. Nature Immunology 2020 Aug;21(8):823-824. doi: 10.1038/s41590-020-0735-0. PMID: 32632290
Stein BD, Calzolari D, Hellberg K, Hu YS, He L, Hung CM, Toyama EQ, Ross DS, Lillemeier BF, Cantley LC, Yates JR, Shaw RJ. Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. Cell Reports 29(10):3331-3348.e7. doi: 10.1016/j.celrep.2019.10.117.PMID: 31801093
Katz ZB, Zhang C, Quintana A, Lillemeier BF*, Hogan PG*. (2019) Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling. Scientific Reports 9(1):10839. doi: 10.1038/s41598-019-46862-w. PMID: 31346209 (*co-corresponding author)
Xie J, Han X, Zhao C, Canonigo-Balancio AJ, Yates JR, Li Y, Lillemeier BF, Altman A. (2019) Phosphotyrosine-dependent interaction between the kinases PKCθ and Zap70 promotes proximal TCR signaling. Science Signaling 12(577):eaar3349. doi: 10.1126/scisignal.aar3349. PMID: 30992398
Katz ZB, Novotná L, Blount A, Lillemeier BF. (2017) A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli. Nature Immunology 18(1):86-95. doi: 10.1038/ni.3631. PMID: 27869819
Davis MM, Krogsgaard M, Huse M, Huppa J, Lillemeier BF, Li QJ (2017) T cells as a self-referential, sensory organ. (2017) Annual Review of Immunology 25:681-95. DOI:10.1146/annurev.immunol.24.021605.090600. PMID: 17291190
Hu YS, Cang H, Lillemeier BF. (2016) Superresolution imaging reveals nanometer- and micrometer-scale spatial distributions of T-cell receptors in lymph nodes. Proceedings of the National Academy of Sciences of the United States of America 113(26):7201-6. doi: 10.1073/pnas.1512331113. PMID: 27303041
Maity PC, Blount A, Jumaa H, Ronneberger O, Lillemeier BF, Reth M. (2015) B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. Science Signaling 8(394):ra93. doi: 10.1126/scisignal.2005887.PMID: 26373673
Klammt C, Novotná L, Li DT, Wolf M, Blount A, Zhang K, Fitchett JR, Lillemeier BF. (2015) T cell receptor dwell times control the kinase activity of Zap70. Nature Immunology 16(9):961-9. doi: 10.1038/ni.3231. PMID: 26237552
Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano AC, Riedel CG, Tanasa B, Klammt C, Fonslow BR, Riera CE, Lillemeier BF, Kemphues K, Yates JR, O’Shea C, Hunter T, Dillin A. (2015) The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. Cell Metabolism 22(1):151-63. doi: 10.1016/j.cmet.2015.06.002. PMID: 26154057
Roh KH, Lillemeier BF, Wang F, Davis MM. (2015) The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck. Proceedings of the National Academy of Sciences of the United States of America 112(13):E1604-13. doi: 10.1073/pnas.1503532112. PMID: 25829544
Klammt C, Lillemeier BF. (2012) How membrane structures control T cell signaling. Frontiers in Immunology 3:291. doi: 10.3389/fimmu.2012.00291. PMID: 23055999
Kasuboski JM, Sigal YJ, Joens MS, Lillemeier BF, Fitzpatrick JA. (2012) Super-resolution microscopy: a comparative treatment. Current Protocols in Cytometry Chapter 2:Unit2.17. DOI: 10.1002/0471142956.cy0217s62. PMID: 23042525
Fitzpatrick JA, Lillemeier BF. (2011) Fluorescence correlation spectroscopy: linking molecular dynamics to biological function in vitro and in situ. Current Opinion in Structural Biology 21(5):650-60. DOI: 10.1016/j.sbi.2011.06.006. PMID: 21767945
Lillemeier BF, Davis MM. (2011) Probing the plasma membrane structure of immune cells through the analysis of membrane sheets by electron microscopy. Methods in Molecular Biology 748:169-82. doi: 10.1007/978-1-61779-139-0_12. PMID: 21701974
Kuhns MS, Girvin AT, Klein LO, Chen R, Jensen KD, Newell EW, Huppa JB, Lillemeier BF, Huse M, Chien YH, Garcia KC, Davis MM. (2010) Evidence for a functional sidedness to the alphabetaTCR. Proceedings of the National Academy of Sciences of the United States of America 107(11):5094-9. doi: 10.1073/pnas.1000925107. PMID: 20202921
Huppa JB, Axmann M, Mörtelmaier MA, Lillemeier BF, Newell EW, Brameshuber M, Klein LO, Schütz GJ, Davis MM. (2010) TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 463(7283):963-7. doi: 10.1038/nature08746. PMID: 20164930
Lillemeier BF, Mörtelmaier MA, Forstner MB, Huppa JB, Groves JT, Davis MM. (2010) TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. Nature Immunology 11(1):90-6. doi: 10.1038/ni.1832. PMID: 20010844
Lillemeier BF, Pfeiffer JR, Surviladze Z, Wilson BS, Davis MM. (2006) Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America 103(50):18992-7. doi: 10.1073/pnas.0609009103. PMID: 17146050
Huse M, Lillemeier BF, Kuhns MS, Chen DS, Davis MM. (2006) T cells use two directionally distinct pathways for cytokine secretion. Nature Immunology 7(3):247-55. doi: 10.1038/ni1304. PMID: 16444260
Kerr IM, Costa-Pereira AP, Lillemeier BF, Strobl B. (2003) Of JAKs, STATs, blind watchmakers, jeeps and trains. FEBS Lett 546(1):1-5. doi: 10.1016/s0014-5793(03)00411-3. PMID: 12829228
Hilkens CM, Is’harc H, Lillemeier BF, Strobl B, Bates PA, Behrmann I, Kerr IM. (2001) A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130. FEBS Lett 505(1):87-91. PMID: 11557047
Lillemeier BF, Köster B, Kerr IM (2001) STAT1 from the cell membrane to the DNA. EMBO J 20:2508-17. PMID: 11350940
van Ham M, van Lith M, Lillemeier B, Tjin E, Grüneberg U, Rahman D, Pastoors L, van Meijgaarden, K, Roucard C, Trowsdale J, Ottenhoff T, Pappin D, Neefjes J. (2000) Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. Journal of Experimental Medicine 191(7):1127-36. PMID: 10748231