Molecular Immunology Lillemeier Laboratory

Projects

Research

Our group is interested in the regulation of lymphocyte activity and function during infections, cancer and autoimmunity. Current research efforts are focused on the activating T cell receptor (TCR) and inhibitory PD1 pathways in T cells. We apply multidisciplinary approaches that combine cutting-edge fluorescence microscopy with biophysics, biochemistry and molecular biology to elucidate how conformations, modifications, localizations and assembly of signaling molecules control signal transduction and thereby T cell activity. Newly identified molecular mechanisms are characterized and targeted in vivo, specifically in mice, to modulate anti-tumor responses and autoimmunity. Our goal is to determine the potential of these novel mechanisms as future drug targets for immunotherapies.

Publications
AG Lillemeier

AG Lillemeier

Prof. Dr. Björn Lillemeier

Biology 3 / CIBSS Excellence Cluster

Albert-Ludwigs-Universität Freiburg

Habsburgerstr. 49

D-79104 Freiburg

Germany

Email (office): miriam.vitt@bioss.uni-freiburg.de

CV Prof. Lillemeier