Molecular Immunology Lillemeier Laboratory

Projects

Research

Our group is interested in the regulation of lymphocyte activity and function during infections, cancer and autoimmunity. Current research efforts are focused on the activating T cell receptor (TCR) and inhibitory PD1 pathways in T cells. We apply multidisciplinary approaches that combine cutting-edge fluorescence microscopy with biophysics, biochemistry and molecular biology to elucidate how conformations, modifications, localizations and assembly of signaling molecules control signal transduction and thereby T cell activity. Newly identified molecular mechanisms are characterized and targeted in vivo, specifically in mice, to modulate anti-tumor responses and autoimmunity. Our goal is to determine the potential of these novel mechanisms as future drug targets for immunotherapies.

We are recruiting! A fully funded EURIDoc PhD position is available in the lab to investigate how to modulate T cell signaling for improved anti-tumor responses in vivo, or how to analyze T cell signaling mechanisms using single molecule microscopy. Information for the interested applicants can be found here.

Full time position for Laboratory Manager/Research Assistant is available in the lab. More information can be found here.

Contact us by email (miriam.vitt@bioss.uni-freiburg.de) if you are interested in working in our lab for your Bachelor’s or Master’s thesis.

 

Publications
AG Lillemeier

AG Lillemeier

Prof. Dr. Björn Lillemeier

Biology 3 / CIBSS Excellence Cluster

Albert-Ludwigs-Universität Freiburg

Habsburgerstr. 49

D-79104 Freiburg

Germany

Email (office): miriam.vitt@bioss.uni-freiburg.de

CV Prof. Lillemeier